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Dingsheng Li, Ph.D.

Associate Professor
Li, Dingsheng

Summary

Dingsheng Li's research assesses human exposure to chemicals and the resulting health risks with various models. He believes by developing these models, chemicals that could pose significant health risks can be identified, providing insights for decision-makers to allocate resources to safeguard the health of society more efficiently. Li is especially interested in using physiologically based pharmacokinetic models to explore the link between external exposures and internal doses. His past and current focus is on nanoparticles and chemicals in consumer products. He is also involved in the development and application of Life Cycle Impact Assessment, which considers the whole life cycle (raw material extraction, manufacturing, packaging, transportation, use and disposal) of products and evaluates the associated impacts.

Research interests

  • Exposure assessment
  • Risk assessment
  • Life cycle assessment
  • Physiologically based pharmacokinetic modeling

Professional affiliations

  • International Society of Exposure Science
  • Society of Environmental Toxicology and Chemistry
  • International Society of Industrial Ecology
  • American Center for Life Cycle Assessment

Selected publications

  • Li, D. & Hicks, A. (2018). Navigating through the challenges to reach life cycle sustainability. Integrated Environmental Assessment and Management (accepted).
  • Fantke, P., Alyward, L., Bare, J., Brown, R., Chiu, W., Dodson, R., Dwyer, R., Ernstoff, A., Howard, B., Jantunen, M., Jolliet, O., Judson, R., Kirchhübel, N., Li, D., Miller, A., Paoli, G., Price, P., Rhomberg, L., Shen, B., Shin, H., Teeguarden, J., Vallero, D., Wambaugh, J., Wetmore, B., Zaleski, R. & McKone, T. (2018). Advancements in life cycle human exposure and toxicity characterization. Environmental Health Perspectives, 126, 125001.
  • Tao, M., Li, D., Song, R., Suh, S. & Keller, A. A. (2018). Framework for modeling the release of chemicals from the use of consumer products. Environmental Pollution, 234, 751–761.
  • Li, D. & Suh, S. (2019). Health risks of chemicals in consumer products: A review. Environment International, 123, 580-587.
  • Tsang, M., Li, D., Garner, K. L., Keller, A. A., Suh, S. & Sonnemann, G. W. (2017). Human health impacts of indoor nanomaterial emissions for life cycle assessment: A case study of titanium dioxide. Environmental Science: Nano, 4(8), 1705-1721. 
  • Fatouraie, M., Eagle, E., Li, D., Morishita, M., Barres, J., Wagner, J. G., Jolliet, O. & Wooldridge, M. (2017). Combustion synthesis of CeO2 nanoparticles for aging and inhalation exposure studies. Journal of Aerosol Science, 106, 24-33.
  • Li, D. & Suh, S. (2017). Health risks of chemicals in consumer products: A review. Environmental Health Perspectives (under review).
  • Tao, M., Li, D., Song, R., Suh, S. & Keller, A. A. (2017). Framework for modeling the release of chemicals from the use of consumer products. Environmental Pollution (under review).
  • Tsang, M., Li, D., Garner, K. L., Keller, A. A., Suh, S. & Sonnemann, G. W. (2017). Human health impacts of indoor nanomaterial emissions for life cycle assessment: A case-study of titanium dioxide. Environmental Science: Nano (accepted). 
  • Li, D., Morishita, M., Wagner, J. G., Fatouraie, M., Wooldridge, M., Eagle, E., Barres, J., Carlander, U., Emond, C. & Jolliet, O. (2016). In vitro biodistribution and physiologically based pharmacokinetic modeling of inhaled fresh and aged cerium oxide nanoparticles. Particle and Fibre Toxicology, 13, 45. >
  • Carlander, U., Li, D., Jolliet, O., Emond, C. & Johanson, G. (2016). Towards a general physiologically based pharmacokinetic (PBPK) model for intravenously injected nanoparticles. International Journal of Nanomedicine, 11, 625-640.
  • Li, D., Johanson, G., Emond, C., Carlander, U., Philbert, M. & Jolliet, O. (2014). Physiologically based pharmacokinetic modeling of polyethylene glycol-coated polyacrylamide nanoparticle in rats. Nanotoxicology, 8(S1), 128-137.
  • Hodas, N., Loh, M., Shin, H., Li, D., Bennett, D., McKone, T. E., Jolliet, O., Weshler, C. J., Jantunen, M., Lioy, P. & Fantke, P. (2015). Indoor inhalation intake fractions of fine particulate matter: Review of influencing factors. Indoor Air.
  • >Li, D., Huijbregts, M. & Jolliet, O. (2015). Life cycle health impacts of polycyclic aromatic hydrocarbons for source-specific mixtures. International Journal of Life Cycle Assessment, 20, 87-99.
  • Wenger, Y., Li, D. & Jolliet, O. (2012). Indoor intake fraction and surface sorption of air organic compounds for life cycle assessment. International Journal of Life Cycle Assessment, 17(7), 919-931.
  • Wu, B., Liu, Z., Xu, Y., Li, D. & Li, M. (2012). Combined toxicity of cadmium and lead on the earthworm Eisenia fetida (Annelida, Oligochaeta). Ecotoxicology and Environmental Safety, 81, 122-126.
  • Rosenbaum, R., Huijbregts, M., Henderson, A., Margni, M., McKone, T., van de Meent, D., Hauschild, M., Shaked, S., Li, D., Gold, L. & Jolliet, O. (2011). USEtox human exposure and toxicity factors for comparative assessment of toxic emissions in life cycle analysis: Sensitivity to key chemical properties. International Journal of Life Cycle Assessment, 16, 710-727.
  • Li, D., Liu, Z. T., Cui, Y. B., Li, W. L., Fang, H., Li, M. & Kong, Z. M. (2011). Toxicity of cyanobacterial bloom extract from Taihu Lake on mouse, Mus musculus. Ecotoxicology, 20(5), 1018-1025.
  • Hu, C. W., Li, M., Cui, Y. B., Li, D., Chen, J. & Yang, L. Y. (2010). Toxicological effects of TiO2 and ZnO nanoparticles in soil on earthworm Eisenia fetida. Soil Biology and Biochemistry, 42(4), 586-591.
  • Li, M., Liu, Z. T., Xu, Y., Cui, Y. B., Li, D. & Kong, Z. M. (2009). Comparative effects of Cd and Pb on biochemical response and DNA damage in the earthworm Eisenia fetida (Annelida, Oligochaeta). Chemosphere, 74(5), 621-625.
  • Li, D., Emond, C., Johanson, G. & Jolliet, O. (2013). Using a PBPK model to study the influence of different characteristics of nanoparticles on their biodistribution. Journal of Physics: Conference Series, 429, 012019.

Education

  • Ph.D. in Environmental Health Sciences, University of Michigan, Ann Arbor, 2015
  • B.S. in Environment Sciences, Nanjing University, 2009